Oral DNA Testing: Our next step in comprehensive care

The OraRisk^® HPV Salivary Diagnostic Test

Human papillomavirus (HPV) is one of the most common virus groups in the world. According to the Centers for Disease Control, at least 20 million people in the United States are infected with HPV and there are approximately 6 million new cases
each year.
Oral HPV is a manifestation of the HPV virus in the mouth, and is primarily found in the oropharyngeal complex. Specific types of oral HPV are now considered to be separate and serious risk factor for developing oral cancers. Early detection and identification of the presence or absence of oral HPV is important, as early oral HPV infections do not typically cause any clinical signs or symptoms.
The OraRisk^® HPV test is a non-invasive, easy-to-use screening tool to identify the type(s) of oral HPV, a mucosal viral infection that could potentially lead to oral cancer. OraRisk^® HPV enables the clinician to establish increased risk for oral cancer and determine appropriate referral and monitoring conditions.

Who should be tested?

• Patients with traditional risk factors for oral cancer
• Patients who are sexually active
• Patients with signs and symptoms of oral cancer
• Patients with suspicious oral lesions

The OraRisk^® HPV test is quickly and easily administered chairside, and takes about a minute to complete. Here’s the process:

1. Patient vigorously swishes and gargles a sterile saline solution for 30 seconds
2. Patient expectorates into funneled collection tube
3. Funnel is removed, cap is secured to top of collection tube
4. Includes standard FedEx^® overnight shipping to OralDNA^® Labs for DNA-PCR analysis
5. E-mail notification is sent to clinician when electronic result report is available

MyPerioPath^®

The MyPerioPath^® salivary diagnostic test identifies the type and concentration of specific perio-pathogenic bacteria that are known to cause periodontal disease. MyPerioPath^® helps support the clinician with better risk assessment and personalized treatment options for more predictable outcomes.

Who should be tested?

• Patients presenting with signs and symptoms of a periodontal infection
• Patients with pockets of 4mm or greater with clinical signs of a periodontal infection
• Patients presenting chronic periodontal disease who are not responding positively to their current treatment
• Patients with Type 1 or Type 2 diabetes
• Patients with a history of cardiovascular disease
• Patients who use tobacco products
• Patients who will undergo surgical procedures or radiation treatment
• Can be used for establishing a “baseline” for any patient who may be at increased risk for periodontal infections
• Patients who test positive for genetic susceptibility with the MyPerioID^® PST^® test
• Women of childbearing age 

The MyPerioPath^® test is quickly and easily administered chairside, and takes about a minute to complete. Here’s
the process:

1. Patient swishes a sterile saline solution for 30 seconds
2. Patient expectorates into funneled collection tube
3. Funnel is removed, cap is secured to top of collection tube
4. Samples are sent via pre-paid FedEx^® envelope to OralDNA^® Labs for DNA-PCR analysis
5. E-mail notification is sent to clinician when electronic result report is available

MyPerioID^® PST^®

The MyPerioID^® PST^® test identifies individual genetic susceptibility to periodontal disease and enables the clinician to establish which patients are at increased risk for more severe periodontal infections due to an exaggerated immune response.

Who should be tested?

• Patients with a family history of periodontal disease
• Patients with compromised immune systems
• Patients that have received therapy but continue with disease activity
• Patients that will receive implants and have lost teeth to periodontal disease
• Adolescent patients

The MyPerioID^® PST^® test is quickly and easily administered chairside, and takes about a minute to complete. Here’s the process:

1. Patient swishes a sterile saline solution for 30 seconds
2. Patient expectorates into funneled collection tube
3. Funnel is removed, cap is secured to top of collection tube
4. Samples are sent via pre-paid FedEx^® envelope to OralDNA^® Labs for DNA-PCR analysis
5. E-mail notification is sent to clinician when electronic result report is available